PURLs
PURLs
Is low-molecular-weight heparin superior to aspirin for VTE prophylaxis?
Aspirin demonstrated a significantly higher rate of postoperative venous thromboembolic events compared with enoxaparin in this noninferiority...
PURLs
A new standard for treatment of torus fractures of the wrist?
A large multicenter trial evaluated effects on pain and function for pediatric patients treated with a soft bandage vs rigid immobilization.
PURLs
Can these salt substitutes prevent complications of hypertension?
This study suggests the blood pressure–lowering effects of potassium-enriched salt substitutes may reduce cardiovascular morbidity and mortality...
PURLs
Should you treat prediabetes? It’s complicated
While treatment with metformin or lifestyle modification reduces risk for T2D in patients with prediabetes, neither intervention ultimately offers...
PURLs
Is injectable PrEP superior to oral therapy for HIV protection?
An RCT of HIV preexposure prophylaxis compared long-acting injectable cabotegravir with traditional daily oral tenofovir-emtricitabine—with clear...
PURLs
Acute Achilles tendon rupture: Skip the surgery?
Nonoperative management for acute Achilles tendon rupture results in patient-reported outcomes similar to surgery at 1 year—but higher rates of...
PURLs
What BP target is appropriate for pregnant patients with mild chronic hypertension?
Active treatment to a lower blood pressure goal (< 140/90 mm Hg) can improve pregnancy outcomes without increasing maternal or fetal risk.
PURLs
Is combination pharmacotherapy effective for patients with acute depression?
A systematic review and meta-analysis found that these combinations were superior to monotherapy and had comparable tolerability.
PURLs
Is self-administered DMPA an answer to contraception access in the post-Roe era?
Compared with provider-administered depot medroxyprogesterone acetate, a prefilled formulation may offer patients improved access to effective...
PURLs
Consider this tool to reduce antibiotic-associated adverse events in patients with sepsis
Predictive biomarker procalcitonin can aid clinical decision-making on continued antibiotic treatment in this patient population.
PURLs
Put down the electronics after a concussion?
Yes, patients should do just that. In a randomized clinical trial, symptom duration was reduced when teens and young adults observed a certain...