PURLs
PURLs
More isn’t better with acute low back pain treatment
Adding cyclobenzaprine or oxycodone/acetaminophen to naproxen for the treatment of acute low back pain does nothing more than increase adverse...
PURLs
“Go low” or say “No” to aggressive systolic BP goals?
The SPRINT trial demonstrated the benefits—and risks—of reaching a systolic target <120 mm Hg in non-diabetic patients at high risk for CV...
PURLs
Resistant hypertension? Time to consider this fourth-line drug
For most adults with resistant hypertension, spironolactone is superior to doxazosin and bisoprolol as an adjunct to triple therapy.
PURLs
Kidney stones? It’s time to rethink those meds
Despite being recommended for ureteral stone expulsion, tamsulosin or nifedipine are no more effective than placebo.
PURLs
Aneuploidy screening: Newer noninvasive test gains traction
Favorable results from the 2 studies reviewed here have prompted ACOG to recommend that cell-free DNA screening be discussed with all pregnant...
PURLs
Should you bypass anticoagulant “bridging” before and after surgery?
Skipping perioperative use of LMWH in low- and moderate-risk patients on warfarin for atrial fibrillation doesn’t increase their risk of stroke or...
PURLs
Sterile or non-sterile gloves for minor skin excisions?
Non-sterile gloves are just as effective as sterile gloves in preventing surgical site infection after minor skin surgeries.
PURLs
This adjunct medication can speed CAP recovery
Adding prednisone to the antibiotic regimen can help patients hospitalized with community-acquired pneumonia to stabilize more quickly and leave...
PURLs
It’s time to reconsider early-morning testosterone tests
Guidelines recommend collecting an early-morning sample to compensate for the natural diurnal variation in testosterone levels. But for men 45 and...
PURLs
Another good reason to recommend low-dose aspirin
Evidence shows that daily low-dose aspirin during pregnancy can safely lower the risk of preeclampsia and other adverse outcomes.
PURLs
Consider these medications to help patients stay sober
Naltrexone can help prevent relapse in recently detoxified patients with alcohol use disorder. The evidence for acamprosate is not quite as strong...