Latest News
Isotretinoin users do not have higher suicide risk: meta-analysis
The analysis showed that the 1-year absolute risk from between two and eight studies of suicide attempts, suicidal ideation, completed suicides,...
Major Depressive Disorder
From the Journals
Pharmacogenomic testing for antidepressants could save time, money
The model found that patients who underwent pharmacogenomic testing spent 15% more time in the “well” state without depression symptoms.
From the Journals
Maternal depressive symptoms may start at pregnancy
“The relevant clinical settings for prevention are those treating women in routine health care, including family medicine.”
Sponsored Supplement
Challenges in Treating Patients with Tardive Dyskinesia
Commentary
Perinatal depression rarely stands alone
Major depressive disorder is the most common mental health condition during the perinatal period and is often comorbid.
From the Journals
Psychedelic therapy tied to reduced depression, anxiety
Study participants reported significant increases in psychological flexibility, cognitive functioning, and postconcussive symptoms.
From the Journals
Air pollution tied to postpartum depression
Black carbon had the strongest association with postpartum depression.
Conference Coverage
Lag in antidepressant treatment response explained?
Compared with the placebo group, participants taking escitalopram had a marked increase in synaptic density.
Conference Coverage
Esketamine bests quetiapine for severe depression in head-to-head trial
“These patients are not resistant, they just have resistance to monoaminergic drugs.”
Commentary
Zuranolone: FAQs for clinicians and patients
Zuranolone was studied in women with severe postpartum depression and had to meet criteria for major depressive disorder no earlier than the third...
From the Journals
Online CBT aids remission of anxiety, depression in students
This precision model, which can also be supported on mobile phones or tablets, could be transferred to primary care facilities or vulnerable...
Hard Talk
The cult of the suicide risk assessment
The rising fascination with repeated suicide risk assessment is misguided in its current form.
Sponsored Supplement
Diagnosing and Managing Tardive Dyskinesia
From the Journals
Psilocybin reduces symptoms, disability in major depression
Significantly more people in the psilocybin group reported at least one treatment-related adverse event (82% vs. 44%), although most were mild to...
From the Journals
Suicidal behavior tied to increased all-cause mortality in MDD
Study suggests that patients at risk for suicidal behavior can be identified at an early stage to allow for enhanced monitoring and optimized...
Families in Psychiatry
The three pillars of perinatal care: Babies, parents, dyadic relationships
Lack of family support is both a predictor and a consequence of perinatal depression.
Opinion
Zuranolone: A novel postpartum depression treatment, with lingering questions
It is noteworthy that while zuranolone received FDA approval for the PPD indication, it did not receive approval for the treatment of major...
From the Journals
Postpartum depression risk increased among sexual minority women
Women identifying as sexual minorities show increases in postpartum depression, yet rates of reporting sexual orientation are low.
From the Journals
Controversial issue of maintenance therapy for bipolar depression still unresolved
“We see a significant benefit for patients who continued treatment with antidepressants.”