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Microemboli play role in certain migraine auras
Key clinical point: A higher prevalence and frequency of microembolic signals were detected in migraine patients with higher cortical dysfunction...
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ASCO: APF530 superior to ondansetron in prevention of CINV
APF530 combined with fosaprepitant and dexamethasone was superior to ondansetron combined with the same agents in the prevention of chemotherapy...
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ASCO: Potentially targetable biomarkers identified in geriatric breast cancer tumors
Multiplatform profiling identified potentially targetable biomarker aberrations in a large sample of tumor taken from older breast cancer patients...
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MRI Improved Breast Cancer Detection in Average-Risk Women
Key clinical point: MRI-screening improved the detection of biologically relevant breast-cancer in women at average risk. Major finding: The...
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ASCO: MRI improved breast cancer detection in average risk women
MRI-screening improved the detection of biologically relevant breast-cancer in women at average risk.
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ASCO: AIs reduce risk of contralateral breast cancer in patients with BRCA mutation
Aromase inhibitors may reduce the rate of contralateral breast cancer in women who already have the disease and are positive for BRCA mutations....
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ASCO: Radiotherapy not needed for all women post mastectomy
Key clinical point: Radiotherapy following mastectomy should not be routinely recommended for breast cancer patients with microscopic nodal...
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Treating women with metastatic breast cancer takes toll
Key clinical point: Many medical oncologists experience the negative emotional impact of their work when treating patients with metastatic breast...
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NLR correlates with survival in advanced breast cancer
Key clinical point: Neutrophil lymphocyte ratio (NLR) can be correlated with poor disease-specific survival in stage IV breast cancer and the...
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No survival difference between continuous and intermittent ADT
Key clinical point: Intermittent androgen deprivation is not inferior to continuous therapy in regards to overall survival.
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Reovirus ready for clinical testing in CLL
Key clinical point: Reovirus, a naturally occurring oncolytic virus, in combination with anti-CD20 immunotherapy, may have benefit for the...
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Mutation testing aids CML treatment decisions
Key clinical point:Mutation testing may aid treatment selection in patients with chronic myeloid leukemia (CML) when selecting an alternative...
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Whole-exome sequencing reveals important mutations in myeloma
Whole-exome sequencing of the patients with myeloma identified 15 significantly mutated genes. With the exception of NRAS and KRAS, the other...
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GM-CSF did not increase survival in high-risk melanoma
Key clinical point: Adjuvant granulocyte macrophage colony-stimulating factor and peptide vaccination did not significantly improve relapse-free...
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Early results encouraging for nivolumab in ovarian cancer patients
Key clinical point: Nivolumab demonstrated encouraging clinical efficacy and tolerability in patients with platinum-resistant ovarian cancer....