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CRC in Lynch syndrome is lower than previously reported
Careful screening of individuals with Lynch syndrome that includes removal of precancerous polyps may keep colorectal cancer rates down.
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Anti-TNF drugs reduce mortality in Crohn’s disease
CHICAGO – As compared to prolonged use of corticosteroids, the use of anti-TNF drugs was associated with reduced mortality in patients with Crohn’...
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Novel agent varlilumab shows activity in RCC
A total of eight patients achieved stable disease in the phase I study, including four with RCC.
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High CD86+pDC counts may predict CML relapses
High CD86+pDC counts predicted relapses in chronic myeloid leukemia patients who stopped TKI therapy.
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Neoadjuvant therapy timing may impact pancreatic cancer outcomes
SEATTLE – Delay between neoadjuvant therapy and surgery may offer some benefit to patients with pancreatic cancer.
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NET can benefit breast cancer patients with delayed surgery
For breast cancer patients whose surgery is delayed, a course of neoadjuvant therapy may be beneficial, but the effectiveness depends on the...
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Atezolizumab improved survival in triple-negative breast cancer
In a phase I trial, the immunotherapy agent atezolizumab improved survival in triple-negative breast cancer.
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Avelumab produces durable responses in Merkel cell carcinoma
“Avelumab could be an important new agent for patients with Merkel cell carcinoma who have failed prior chemotherapy,” said Dr. Howard L. Kaufman...
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Nivolumab boosts 5-year survival in advanced NSCLC
Treatment with nivolumab resulted in a 5-year overall survival rate that is much higher than what is reported for this patient population...
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Dual targeting effective in HER2+ metastatic colorectal cancer
A combination of two drugs resulted in a 30% objective response rate in heavily pretreated patients with HER2-positive metastatic colorectal...
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Safe to avoid sentinel node biopsy in some breast cancer patients
SEATTLE – Sentinel node biopsy can be safely avoided in certain populations of breast cancer patients.
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Preoperative VTEs occurred in 10% of cancer patients
SEATTLE – Those with preoperative VTEs were significantly more likely to experience postoperative complications.
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Disease site determines QOL, pain in recurrent rectal cancer
SEATTLE – Posterior recurrence was associated with the worst quality of life and most severe pain.
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Cardiovascular disease most common cause of death in CRC survivors
SEATTLE – Colorectal cancer is not the most likely cause of death in long-term CRC survivors.
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Outcomes of neoadjuvant therapy vary by subtype in bladder cancer
Clinical outcomes for neoadjuvant chemotherapy vary by molecular subtype in muscle-invasive bladder cancer.