Hematology
Video
VIDEO: Search for genetic risk factors may improve vincristine therapy
News
Genetic variant predisposes to vincristine-related neuropathy
Key clinical point: A variation in the CEP72 gene appears to predispose carriers to develop peripheral neuropathy when they are treated with...
News
Consent and the mature minor
Conference Coverage
CAR-T cell therapy rolls on in pediatric ALL
Key clinical point: CAR-T cell therapy continues to provide durable responses in early studies of children with refractory ALL. Major finding:...
News
FDA advisers support pediatric studies of three investigational oncology agents
Conference Coverage
Young adults with ALL have better survival with pediatric regimens
Key clinical point: Adolescents and young adults with acute lymphoblastic leukemia should be treated with a pediatric rather than an adult ALL...
News
Sickle cell anemia trial halted because of early success
Conference Coverage
Blood cultures offer little benefit to children with CAP
Key clinical point: Blood cultures in children with community-acquired pneumonia (CAP) are not free of harm. Major finding: Children in the blood...
Guidelines
NHLBI expert panel issues guideline on sickle cell disease
Major finding: The two most widely available disease-modifying therapies for SCD, hydroxyurea and long-term transfusions, are underused, in large...
From the Journals
NHLBI expert panel issues guidelines on sickle cell disease
The “much anticipated” guideline to help primary-care and emergency clinicians improve the management of sickle cell disease includes a consensus...