Non-Hodgkin Lymphoma
News
NICE recommends pixantrone for NHL
Credit: Bill Branson Counter to its previous recommendations, the UK’s National Institute for Health and Care Excellence (NICE) is now supporting...
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FDA approves ibrutinib for previously treated MCL
The US Food and Drug Administration (FDA) has has granted accelerated approval for ibrutinib (Imbruvica) to treat patients with mantle cell...
News
Company suspends enrollment in drug trials
Credit: Esther Dyson After 2 deaths among patients receiving the BCL-2 inhibitor ABT-199, the company developing the drug has suspended...
News
CD19-redirected T cells induce remission in CLL patients
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FDA warns of possible link between breast implants and ALCL
People with breast implants “may have a very small but significant risk of ALCL in the scar capsule adjacent to the implant,” according to the...
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Denileukin diftitox has significant, durable responses in CTCL
The recombinant fusion protein denileukin diftitox (DD) produced a significant and durable overall response rate at 2 dose levels as compared to...
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Fostamatinib successfully targets the B-cell receptor
The B-cell receptor is present on both normal B cells and malignant B cells. Signaling through this receptor is necessary for B-cell maturation...
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Ofatumumab receives accelerated approval from FDA
The drug was approved under the FDA’s accelerated approval process, which allows drugs that meet unmet medical needs to be approved faster.
News
Potential cause of R-CHOP failure ruled out
Researchers say they have come one step closer to determining the cause of R-CHOP failure in diffuse large B-cell lymphoma (DLBCL) by ruling out a...