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Belimumab for pregnant women with lupus: B-cell concerns remain
The largest combined analysis of birth outcome data found no apparent increase in birth defects or pregnancy loss with belimumab, and a separate...
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GOLD Report 2023: Important updates and revisions
Among the updates, the section on diagnostic criteria added a proposed new category “PRISm,” encompassing individuals who present with structural...
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Doctor urges compassionate access to specialized radiotherapy for inoperable RCC
SABR should be considered for patients with larger, inoperable kidney cancers who have no treatment options.
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Newer agents for nosocomial pneumonia: The right drug for the right bug
“The right drug at the right time with the right dose for the right bug for the right duration.”
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Skinny-label biosimilars provide substantial savings to Medicare
The estimated savings to Medicare during 2015-2020 that resulted from competition with five of the first-to-market biosimilars with skinny labels...
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In rheumatoid arthritis, reducing inflammation reduces dementia risk
Compared with conventional synthetic disease-modifying antirheumatic drugs, biologic/targeted synthetic DMARDS lower dementia risk.
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Race and gender: Tailoring treatment for sleep disorders is preferred and better
Sleep disparities are multifactorial and it is important to focus on social determinants of poor sleep.
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Achieving diversity, equity and inclusion: Invite everyone and build a team
Don’t recruit diverse people to your program and then have them come and feel not included.
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Airway structure in women leads to worse COPD outcomes
Worse COPD outcomes found for women for each unit change in wall thickness or lumen area.
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COVID-19 and IPF: Fundamental similarities found
“This biomarker could indicate who is at greatest risk for progressive fibrosis.”
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Immune checkpoint and VEGF inhibitors superior in renal cell carcinoma treatment
This combination treatment led to longer overall survival than with doublet immune checkpoint blockade.
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Analysis shows no benefit for cytoreductive nephrectomy
Observational studies of metastatic clear cell renal cell carcinoma fail to adjust for bias.
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Study confirms BRCA1 and BRCA2 linked to seven cancers
Some associations are stronger than others with biliary tract, esophageal, and gastric cancers rising to the top.
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Head and neck tumor grade may predict response to immunotherapy
Small study shows that high-grade head and neck tumors, not low grade, may be better suited for immunotherapy.