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    • Deprecated function: Return type of DatabaseStatementBase::execute($args = [], $options = []) should either be compatible with PDOStatement::execute(?array $params = null): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2246 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
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    Rif S. El-Mallakh, MD

    Article

    Interventional psychiatry

    Interventional psychiatry (Part 2)

    Author:
    Dmitry M. Arbuck, MD
    Ali A. Farooqui, MD
    Rif S. El-Mallakh, MD

    Neuromodulation may be an effective option for some patients with difficult-to-treat conditions.

    • Read More

    Article

    Kathy Vincent, MD

    Interventional psychiatry: What are the next steps?

    Author:
    Kathy Vincent, MD
    Megan Good, MD
    Rif S. El-Mallakh, MD

    The explosion of interest in interventional psychiatry is highlighted by 2 recent reviews published in Current Psychiatry.

    • Read More

    Article

    Interventional psychiatry

    Interventional psychiatry (Part 1)

    Author:
    Dmitry M. Arbuck, MD
    Ali A. Farooqui, MD
    Rif S. El-Mallakh, MD

    For some patients, IV medications, blocks, and injections could be effective treatments.

    • Read More

    Article

    Bipolar disorder

    Bipolar disorder: The foundational role of mood stabilizers

    Author:
    Bhumika Shah, MD
    Omar H. Elsayed, MD
    Rif S. El-Mallakh, MD

    Bipolar disorder (BD) is a recurrent, life-long psychiatric illness affecting nearly 2% of the world population that is characterized by episodes...

    • Read More

    Article

    Woman taking pill

    Adaptive changes to antipsychotics: How to avoid the consequences

    Author:
    Ahmad Sleem, MBBCh
    Rif S. El-Mallakh, MD

    While our understanding of the mechanisms of psychosis continues to evolve beyond the dopamine hypothesis, the key role...

    • Read More

    Article

    Serotonin-mediated anxiety: How to recognize and treat it

    Author:
    Sara R. Abell, MD
    Rif S. El-Mallakh, MD

    Individuals with anxiety will experience frequent or chronic excessive worry, nervousness, a sense of unease, a feeling of being unfocused, and...

    • Read More

    Article

    Kidney

    Lithium and kidney disease: Understand the risks

    Author:
    Ziad A. Ali, MD
    Rif S. El-Mallakh, MD

    Lithium is one of the most widely used mood stabilizers and is considered a first-line treatment for bipolar disorder because of its proven...

    • Read More

    Article

    Old woman laying in bed

    Suvorexant: An option for preventing delirium?

    Author:
    Saba Afshar, MBBS
    Kathryn Marcellus, MD
    Rif S. El-Mallakh, MD

    Recent evidence suggests that suvorexant, which is FDA-approved for insomnia, may be useful for preventing delirium.

    • Read More

    Article

    Woman sitting under blanket near lamp

    Posttraumatic stress disorder: From pathophysiology to pharmacology

    Author:
    Bilge Togay, MD
    Rif S. El-Mallakh, MD

    PTSD occurs acutely and chronically in the aftermath of severe and potentially life-threatening trauma.

    • Read More

    Article

    Rif S. El-Mallakh, MD

    Receptor occupancy and drug response: Understanding the relationship

    Author:
    Rif S. El-Mallakh, MD

    Most clinicians do not think about receptor occupancy when they prescribe a medication. Most simply assume that if they use a low dose of a...

    • Read More

    Article

    Understanding the brexpiprazole therapeutic window: Why more isn’t always better

    Author:
    Anjali Dhanda, MD
    Zachary Sager, MD
    Rif S. El-Mallakh, MD

    Dosage windows could be difficult to understand pharmacologically, but for a partial agonist the presumed mechanism could be more evident....

    • Read More

    News

    How coffee and cigarettes can affect the response to psychopharmacotherapy

    Author:
    Anoop Narahari, MD
    Rif S. El-Mallakh, MD
    Murali K. Kolikonda, MD
    Amandeep Singh Bains, MD
    Steven Lippmann, MD
    • Read More

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