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Subcutaneous ketamine for TRD practical, safe, and highly effective
“Individualized dose adjustment, based on clinical response, was very important in optimizing the benefit of ketamine,” said Dr. Colleen Loo.
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Novel talk therapy challenges CBT for treating anhedonic depression
The primary focus of ADepT is building well-being (capacity to experience pleasure, meaning, and social connection in life) and functional...
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Cognitive benefit of highly touted MIND diet questioned
“Although we did not see a specific effect of the MIND diet, people in both groups improved their cognitive function.”
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Omega-3s and AFib: No added risk from eating fish but high-dose supplement questions persist
The current study is “important in showing that physiologic levels of omega-3s that would accumulate through diet don’t seem to increase the risk...
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Chronic constipation linked to cognitive decline
“These results stress the importance of clinicians discussing gut health, especially constipation, with their older patients.”
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A risk for adverse events in cancer meds cleared renally
“We found a considerably higher rate of supratherapeutic drug levels and [adverse events] associated with select renally cleared medication.”
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Opioid initiation in dementia tied to an 11-fold increased risk of death
Especially in elderly patients, the risks and benefits of initiating opioid therapy should be carefully considered.
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‘Brain fitness program’ may aid memory loss, concussion, ADHD
Study findings “appear to show that multimodal interventions which are known to increase neuroplasticity in the brain, when personalized, can have...
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Immunotherapy stewardship could save tens of millions a year
“Why should we give a higher dose with the same efficacy when that dose will cost significantly more and has the potential to increase adverse...
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Fatigue after breast cancer radiotherapy: Who’s most at risk?
Risk factors, including pain, insomnia, depression, baseline fatigue, and endocrine therapy, were associated with long-term fatigue, new data show...
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Metachronous CRC risk after colonoscopy for positive FIT
“Results of this study could contribute to establish more restrictive polyp surveillance guidelines in a quality-assured setting.”
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Liquid biopsy shows big promise in oropharyngeal cancer
“The use of this technology shows remarkable promise to transform the ability to identify and follow patients with HPV-related disease.”
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End of the road for transcranial brain stimulation as an adjunct in major depression?
These findings call into question the efficacy of tDCS as add-on therapy to SSRI treatment for individuals with MDD.
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Schizophrenia up to three times more common than previously thought
An estimated 11 million adults aged 18-65 had both a mental health disorder and a substance use disorder in the past year.
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Smartwatches able to detect very early signs of Parkinson’s
With these results we could develop a valuable screening tool to aid in the early detection of Parkinson's," one of the investigators said.