Article
Early mortality risk factors in adult sickle cell disease support ECG screening
The largest combined analysis of mortality risk factors for adult sickle cell disease patients in the era of hydroxyurea use confirms previous...
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Annual nailfold videocapillaroscopy found prognostic in systemic sclerosis
Features of nailfold videocapillaroscopy in systemic sclerosis patients can be used to predict overall disease progression over the course of...
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Nonthoracic MRI safe in patients with cardiac devices
Nonthoracic MRI was safe in patients who had implanted non–MRI-conditional pacemakers or ICDs, as long as they followed a specific safety protocol...
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Lanadelumab reduced hereditary angioedema attacks by 88%-100%
Lanadelumab reduced attacks of hereditary angioedema with C1 inhibitor deficiency by 88%-100%.
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Osimertinib helps NSCLC that progresses despite EGFR-TKIs
Osimertinib yielded a high overall response rate, “encouraging” progression-free survival, and a durable treatment response in advanced non–small...
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Hormone therapy prolongs PFS in rare low-grade serous cancer
Hormone maintenance therapy given after primary cytoreductive surgery and platinum-based chemotherapy prolonged progression-free survival among...
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Light therapy eases Parkinson’s-related sleep disturbances
A pilot randomized controlled study in Parkinson’s disease patients shows that light therapy shows promise for reducing daytime sleepiness and...
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More periviable infants survive without neurodevelopmental impairment
What percentage of periviable infants can survive without impairment?
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RA-BEAM trial shows that baricitinib improves RA symptoms, slows joint damage
Results of the phase III RA-BEAM trial indicate that the JAK inhibitor baricitinib has superior efficacy over placebo and adalimumab when taken in...
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Low-back pain: CBT, mindfulness benefits diminish over time
The benefits of mindfulness practice and cognitive-behavioral therapy on low-back wane over time.
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C. auris forms biofilms, enhancing its virulence, resistance
The emerging multidrug-resistant yeast organism Candida auris forms biofilms that enhance both its resistance and its virulence, according to in...
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Peripheral B cells reflect intestinal damage in celiac disease
A gluten challenge study found a nuanced B-cell response.
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MDS gene mutations predict response to HSCT
Genetic mutations in blood samples may predict outcomes and guide treatment for patients of all ages who have myelodysplastic syndrome and are...
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Sickle cell trait artificially lowers HbA1c
HbA1c levels systematically underestimate glucose levels in black patients who carry the sickle cell trait, researchers say.
Article
Guideline: CRC patients should receive RAS mutation testing
A new clinical practice guideline published in the Journal of Clinical Oncology supports testing colorectal cancers for genetic mutations in the...