News
CSF lactate concentration identifies postneurosurgical bacterial meningitis
Key clinical point: CSF lactate concentration accurately identifies bacterial meningitis that develops after neurosurgery. Major finding: CSF...
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Buprenorphine restrictions don’t hinder addiction therapy
Key clinical point: Restrictions on the number of buprenorphine prescriptions a physician can write in a given year do not hinder addiction...
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ASCO updates postmastectomy radiotherapy guideline
Key clinical point: The ASCO clinical practice guideline on postmastectomy radiotherapy has been updated to help clinicians decide which patients...
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Four factors raise risk of post-TAVR endocarditis
Key clinical point: Four factors raise the risk that patients undergoing transcatheter aortic valve replacement will develop infective...
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Smoking thickens LV wall, worsens function
Key clinical point: Current smoking was associated with higher left ventricular mass, a higher LV mass-to-volume ratio, and worse diastolic...
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Lowering LDL-C yields usual benefits in rheumatoid arthritis
Key clinical point: Lowering LDL cholesterol yields the same cardiovascular benefits in rheumatoid arthritis patients as in the general population...
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Soccer injuries up 111% in children
The increase in soccer-related injuries was much greater among girls than among boys, paralleling the much larger increase in soccer participation...
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Drug combo shows promise for non–clear cell renal cell carcinoma
Key clinical point: The combination of everolimus plus bevacizumab showed promise against advanced non–clear cell renal cell carcinoma...
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High free T4 levels linked to sudden cardiac death
High levels of free thyroxine are associated with an increased risk of sudden cardiac death, even in euthyroid adults.
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Whole brain radiotherapy not beneficial for NSCLC metastasis
Whole brain radiotherapy provided no clinically significant benefit for most patients with metastatic non–small-cell lung cancer.
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Antibiotic susceptibility differs in transplant recipients
Antibiotic susceptibility in bacteria cultured from transplant recipients at a single hospital differed markedly from that in hospital-wide...
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Adding salmeterol to steroids didn’t boost kids’ serious asthma events
Adding salmeterol to fluticasone therapy didn’t increase serious asthma-related events among children.
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Adding formoterol to budesonide does not increase serious asthma events
Key clinical point: Adding formoterol to budesonide in a fixed-dose combination does not increase serious asthma-related events in adolescents and...
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Off-hours timing does not affect PCI outcomes
Key clinical point: Off-hours presentation to the hospital with STEMI didn’t affect PCI outcomes in a large international trial. Major finding:...
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NSTEMI mortality decline attributed to invasive therapies
Key clinical point: Invasive coronary therapies largely account for the decade-long decline in mortality among patients hospitalized in the U.K....