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‘Smart’ stethoscope spots peripartum cardiomyopathy
Finding that 4% of the women in the intervention arm had reduced ejection fraction is “absolutely startling ... and speaks to how important...
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Better postpartum BP control with self-monitoring: POP-HT
“This trial identifies a potential need for a paradigm shift in the way women affected by hypertensive pregnancy are managed postnatally,” said Dr...
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In MI with anemia, results may favor liberal transfusion: MINT
This study is “not a home run,” for the primary outcome, however, many of the outcomes tended to be in favor of a liberal transfusion strategy.
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Newer antiobesity meds lower the body’s defended fat mass
“These medications change [the defended fat mass] to something that is more normal, rather than ‘fixing’ it.”
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Beyond semaglutide, a coming pipeline of new antiobesity meds
With the two highest doses of retatrutide, 100% of participants lost ≥ 5% of weight. “I’m not sure how many other times I will ever be able to say...
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What predicts successful weight loss maintenance in WeightWatchers?
Future interventions to prevent weight regain should target overeating in response to internal and external food cues and declines in self-...
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Antidepressants ‘don’t blunt’ semaglutide and weight loss
“Semaglutide 2.4 mg provides an effective treatment option for weight management, regardless of antidepressant use at baseline.”
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Alert! A decade of type 2 diabetes shortens life by 3.5 years
“I personally think the findings show that we should treat cardiovascular risk factors more aggressively in people diagnosed with [type 2]...
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Optimal antiplatelet regimen in ‘bi-risk’ ACS?
OPT-BIRISK tested an antiplatelet strategy “in challenging patients at increased risk for bleeding and ischemic events, but I don’t think we can...
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Longer edoxaban may benefit cancer patients with distal DVT
“This is the first and only randomized trial to show the superiority of longer duration over shorter duration of anticoagulation therapy for...
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Muvalaplin and olpasiran show early promise in lowering Lp(a)
“For the first time we have an oral agent” that lowers Lp(a) levels. However, “we will still need to determine if this leads to a reduction in...
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Cardiac arrest centers no benefit in OHCA without STEMI
On the other hand, patients with MI “will benefit from going straight to a heart attack center and having an attempt at reopening the artery.”
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ESC issues new guidelines on infective endocarditis
Diagnosing a lethal, rare, but not uncommon disease such as endocarditis “is something that clinicians struggle with every day,” he noted,...
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Lower is better for blood glucose to reduce heart disease
“We uncovered compelling evidence that for blood sugar levels within the ‘normal’ range, it was a case of ‘the lower the better’ in protecting...
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Certain genes predict abdominal fat regain after weight loss
“These findings are the first of their kind and provide new insights into the mechanisms of weight regain.”