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Greater fracture risk reduction seen with denosumab vs. zoledronic acid in postmenopausal women
The analysis took extra pains to remove bias through data that might be linked to potential confounders but could not reasonably be attributed to...
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Biologics linked to fewer hospitalizations after asthma exacerbation
The study adds to growing data that biologics offer better long-term outcomes and could reduce health care utilization.
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Short, long-lasting bronchodilators similar for exacerbated COPD
Long-lasting bronchodilators are recommended by the Gold Report, but clinical evidence was lacking in this population.
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Nivolumab/Ipillimumab combo demonstrates long-term efficacy in NSCLC
“Most importantly, approximately 50% of these patients that are alive at six years are also disease free, suggesting that we are indeed making a...
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Neoadjuvant durvalumab does not affect surgical outcomes in NSCLC: Study
AEGEAN is one of the first studies looking at immune checkpoint inhibitors in the perioperative settings that demonstrated improved EFS and pCR...
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Surgery may worsen pleural mesothelioma survival outcomes
The first randomized, controlled trial shows greater mortality than chemotherapy alone, though surgical expertise may be a confounder.
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ADCs show early promise in NSCLC
“ADCs are a new, rapidly evolving class of therapeutics, and I think that we will all have to be prepared for the future that is coming,” said Dr...
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What is the proper treatment for posttraumatic headache? Expert debate
Preventative treatment could reduce chronification, but has the potential to worsen comorbidities.
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Prodrome treatment with ubrogepant prevents migraines
Intervention also reduced prodromal symptoms in patients who could reliably predict oncoming headaches.
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Migraine treatment with rimegepant linked to reduced barbiturate use
Real-world analysis suggests potential for improvements in medication overuse and dependency.
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Migraine device expands treatment possibilities
New studies of remote electrical neuromodulation show efficacy in adolescents and safety during pregnancy.
Article
Cannabis RCT shows efficacy, AEs in migraine
First RCT in migraine suggests THC/CBD mix might be best, and that recreational doses may be higher than necessary.
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Migraine clusters emerge from machine-learning analysis
Groupings somewhat reflect expert consensus, but also suggest therapeutic avenues.
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New study backs up capecitabine dosing practice in metastatic BC
Study finds similar progression-free and overall survival in 7-day-on/7-day-off schedule, with fewer side effects than 14 days on, 7 days off.
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In TNBC, repeated biopsies may reveal emergent HER2-low expression
Results could broaden eligibility for treatment with the antibody-drug conjugate trastuzumab deruxtecan.