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VIDEO: Liraglutide acts on GLP-1 receptors to lessen desire for high-fat foods
Liraglutide may work to decrease activation of brain sites related to desire for unhealthy foods in patients with type 2 diabetes.
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Faster aspart speeds onset of activity in Type 1 diabetes
Key clinical point: As a faster-acting mealtime insulin, faster aspart may mimic more closely the physiologic mealtime insulin response of the...
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Brain atrophy may be a clinically relevant measure in PPMS: Data from INFORMS
Key clinical point: Brain atrophy could be a clinically useful and relevant measure in primary progressing multiple sclerosis.
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Fingolimod improved gait impairment in small study
Key clinical point: Fingolimod shows signs that it may improve gait in MS patients who are naive to treatment or have only received first-line...
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Ocrelizumab subanalysis hints at better efficacy with active inflammatory lesions
Key clinical point: Certain subgroups of patients may respond better to treatment Major finding: Reduction in the risk of confirmed disability...
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Blood-borne biomarkers of MS relapse identified
Key clinical point: Blood-borne biomarkers of MS relapse and treatment efficacy were identified. Major finding: RGC-32, FasL, and IL-21 are...
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Treatment justified even for moderately advanced MS disability
Treatment for MS should continue even when disability is advanced.
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Potential biomarkers of gray matter damage in MS identified
The pattern of the CSF biomarkers, which correspond to the extent of gray matter damage, has potential value in stratifying patients in terms of...
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ACTRIMS: Ovarian decline linked to MS progression in women
Key clinical point: Anti-m<scaps>ü</scaps>llerian hormone may be a biologic marker of MS progression in women.
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ACTRIMS: Treadmill exercise transiently benefits cognition in MS patients
Treadmill exercise can at least transiently improve cognitive impairment in patients with multiple sclerosis.
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ACR: Investigational lupus drugs test new or reworked approaches to treatment
A variety of new, repurposed, and reformulated compounds have made their way into clinical trials for systemic lupus erythematosus, including a...
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Riociguat deemed suitable for PAH in connective tissue disease
Key clinical point: Patients with pulmonary arterial hypertension and connective tissue disease can benefit from riociguat treatment. Major...