GI Oncology
Article
Study reveals how aspirin may inhibit colorectal cancer
Aspirin rescued a proneoplastic intestinal phenotype, reduced stem cell expression and function, and increased the expression of an important Wnt...
From the Journals
Younger adults present with more advanced esophageal adenocarcinoma
The incidence of esophageal adenocarcinoma has risen threefold over the past 4 decades among patients younger than 50 years.
From the Journals
PDAC: Tumor reduction after neoadjuvant therapy may predict postsurgical survival
A 47% or more reduction in tumor size between endoscopic ultrasound and surgery predicted 3- and 5-year survival in pancreatic ductal...
From the Journals
Geography and behaviors linked to early-onset colorectal cancer survival in U.S. women
Physical inactivity and lower fertility correlate modestly with early-onset colorectal cancer mortality in women.
From the Journals
Pembrolizumab ‘preferred choice’ in MSI-H/dMMR metastatic CRC
Compared with chemotherapy, pembrolizumab doubled progression-free survival and improved the overall response rate in this patient population.
From the Journals
Hemochromatosis variants may confer 10-fold higher risk of liver cancer
Men of European ancestry had a greater risk of liver cancer and death if they had HFE variants.
Conference Coverage
Rapid relief of opioid-induced constipation with MNTX
Subcutaneously administered, peripherally acting mu-opioid receptor antagonist, relieves opioid-induced constipation in both chronic, noncancer-...
From the Journals
Task force recommends best practices for malignant colorectal polyps
Endoscopists should look for features of deep submucosal invasion and should retrieve, handle, and submit specimens in ways that support thorough...
Conference Coverage
Statins may lower risk of colorectal cancer
Patients with IBD who used statins had a 60% lower risk of CRC.
Guidelines
Now USPSTF also suggests start CRC screening at age 45
But the benefit for screening adults in the 45- to 49-years age group is smaller than it is for adults aged 45-75 years.
Latest News
Novel imaging technique finds more neoplastic GI lesions
Linked color imaging detected upper gastrointestinal tumors more effectively than standard white light