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Transcatheter tricuspid valve repair effective and safe for regurgitation
In a randomized pivotal trial, a percutaneous repair of tricuspid valve regurgitation was effective and safe.
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At 5 years, TAVI valves perform better than surgical ones
TAVR valves deteriorate less than surgical valves at 5 years in patients treated for severe aortic stenosis.
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Risk of stent infection low, but may be underreported
The systematic review of coronary stent infections leads investigator to question whether they are underreported.
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In weighing PCI vs. CABG for left main disease, diabetes matters
In patients with diabetes and left main artery disease, the risks of PCI and CABG are different when either can be used.
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Drinking beet juice tied to reduced post-PCI restenosis
Dietary nitrate in the form of beet juice reduced restenosis after percutaneous interventions in a randomized trial.
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New tool better estimates cardiovascular risk in people with lupus
A tool to estimate cardiovascular risk in systemic lupus erythematosus incorporates disease-specific variables.
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PsA prediction tool approaches clinical utility
A tool to identify patients with psoriasis at high risk of psoriatic arthritis appears near to clinical application.
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Two biomarkers identify high-risk lupus nephritis
Two biomarkers, elastase-DNA and HMGB1-DNA, correlate with poor outcomes in patients with lupus nephritis.
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Biosimilars perform identically to originator biologics in natural experiment
A real-world analysis of the impact of biosimilar switches over 3 years of follow-up addresses the limitations of formal trials in assessing...
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Elevated PCSK9 levels associated with psoriasis suggest new treatment target
A large population analysis implicates PCSK9 as a target in prevention of psoriasis.
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After PCI, 1-month beats 12-month DAPT in high-risk patients
When dual was replaced by single antiplatelet therapy 1 month after PCI in Japanese patients, bleeding risk declined.
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Study supports banning probiotics from the ICU
The risk is particularly acute for powdered formulations, presumably because powder more easily disseminates to contaminate central venous...
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Sham-controlled renal denervation trial for hypertension is a near miss
The SPYRAL HTN–ON MED trial missed its primary endpoint, likely caused in part by imbalances in medication use.
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First-line AFib ablation cuts risk of progression vs. drug therapy
Atrial fibrillation treated with ablation rather than drug therapy was less likely to progress to persistent symptoms in the PROGRESSIVE-AF trial...
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If a saphenous graft is available, treat limb threatening ischemia surgically
Surgery beats endovascular treatment for limb threatening ischemia when saphenous grafts are an option, according to the BEST-CLI trial.