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    • Deprecated function: Return type of DatabaseStatementBase::execute($args = [], $options = []) should either be compatible with PDOStatement::execute(?array $params = null): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2246 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::current() should either be compatible with Iterator::current(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::next() should either be compatible with Iterator::next(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::key() should either be compatible with Iterator::key(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::valid() should either be compatible with Iterator::valid(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::rewind() should either be compatible with Iterator::rewind(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).

    Mark S. Lesney, PhD

    News

    Polygenic risk score may predict VTE in adolescents, but not adults, with ALL

    Author:
    Mark S. Lesney, PhD
    Publish date: August 14, 2020

    A genetic risk score predicted which acute lymphoblastic leukemia–affected adolescents were more at risk of a...

    • Read More

    News

    Elotuzumab-based therapy may benefit post-transplant response in multiple myeloma

    Author:
    Mark S. Lesney, PhD
    Publish date: August 12, 2020

    Elotuzumab-based maintenance may deepen response post transplant in MM and can be safely administered in older...

    • Read More

    News

    BALL score predicts benefit from ibrutinib therapy in relapsed/refractory CLL patients

    Author:
    Mark S. Lesney, PhD
    Publish date: August 11, 2020

    The BALL score outperformed three other scores in providing the best prediction of an overall survival benefit...

    • Read More

    Opinion

    Chronicles of cancer: A history of mammography, part 1

    Author:
    Mark S. Lesney, PhD
    Publish date: August 7, 2020

    Tied to the rise of technology and the women's rights movement, the story of mammography is a touchstone for the history of cancer screening and...

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    News

    Posaconazole prophylaxis was effective in children with ALL undergoing chemotherapy

    Author:
    Mark S. Lesney, PhD
    Publish date: August 7, 2020

    Targeted posaconazole prophylaxis was effective in preventing invasive fungal infection in children with ALL undergoing induction chemotherapy.

    • Read More

    News

    MM patients with concurrent AL show poor survival when coupled to cardiac dysfunction

    Author:
    Mark S. Lesney, PhD
    Publish date: July 23, 2020

    Cardiac dysfunction is a major determinant of poor survival in multiple myeloma patients with concurrent light chain amyloidosis.

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    News

    HSCT or systemic treatment should be offered to HIV+ patients with lymphoma

    Author:
    Mark S. Lesney, PhD
    Publish date: July 16, 2020

    Patients with lymphoma and HIV infection benefit from systemic or stem cell therapy, but with worse outcomes...

    • Read More

    News

    Heavy menstrual bleeding difficult to control in young patients with inherited platelet disorders

    Author:
    Mark S. Lesney, PhD
    Publish date: July 10, 2020

    Consensus and a broadly effective treatment for heavy menstrual bleeding was not found among the patients with inherited platelet function...

    • Read More

    News

    Transitioning regimen may prolong proteasome inhibitor–based therapy for MM

    Author:
    Mark S. Lesney, PhD
    Publish date: July 9, 2020

    Transitioning from parenteral bortezomib-based induction to all-oral ixazomib-lenalidomide-dexamethasone increased PI-based treatment adherence/...

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    News

    FDA approves selinexor for relapsed/refractory DLBCL

    Author:
    Mark S. Lesney, PhD
    Publish date: June 23, 2020

    Selinexor is approved for adults with relapsed/refractory DLBCL, including DLBCL arising from follicular...

    • Read More

    News

    Oxidatative stress–related genetic variant tied to stroke risk in sickle cell patients

    Author:
    Mark S. Lesney, PhD
    Publish date: June 23, 2020

    SOD2 Val16Ala polymorphism may represent a simple and inexpensive alternative for identifying sickle cell patients at risk of stroke.

    • Read More

    News

    First-in-kind anti-CD47 antibody shows promise for MDS and AML treatment

    Author:
    Mark S. Lesney, PhD
    Publish date: June 19, 2020

    Magrolimab/azactydine (AZA) improved outcomes in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS...

    • Read More

    News

    Subcutaneous hep A vaccination as effective as intramuscular for bleeding disorder patients

    Author:
    Mark S. Lesney, PhD
    Publish date: June 12, 2020

    Subcutaneous hepatitis A vaccination is as effective and may be safer for patients with bleeding disorders....

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    News

    Added rituximab was effective in children and adolescents with high-risk B-cell NHL

    Author:
    Mark S. Lesney, PhD
    Publish date: June 3, 2020

    Adding rituximab to chemotherapy was effective in children and adolescents with high-risk, high-grade, mature B-...

    • Read More

    News

    Acute lymphoblastic leukemia can be successfully treated in the frail elderly

    Author:
    Mark S. Lesney, PhD
    Publish date: June 3, 2020

    Attenuated chemotherapy shows effectiveness in frail and elderly ALL patients.

    • Read More

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