News
Investigational CDK4/6 inhibitor shows activity, less toxicity
Key clinical point: A phase I trial indicates that abemaciclib is safe and shows activity in treating patients with advanced breast and other...
News
Exercise linked to fewer cardiovascular events in nonmetastatic breast cancer patients
Key clinical point: Exercise was linked to significantly reduced risk of cardiovascular events in women with nonmetastatic breast cancer,...
News
Dasatinib bests imatinib on molecular, cytogenic response rates in CML
Key clinical point: Patients with chronic myeloid leukemia who received dasatinib experienced higher rates of major molecular response and...
News
Exercise Linked to Fewer Cardiovascular Events in Nonmetastatic Breast Cancer Patients
Key clinical point: Exercise was linked to significantly reduced risk of cardiovascular events in women with nonmetastatic breast cancer,...
News
Liquid biopsy–based test detects BRAF mutations
Key clinical point: Analysis of plasma-derived cfDNA can identify BRAF mutations as accurately as FFPE tumor sample analysis. Major finding:...
News
‘Extreme’ monitoring fails to boost survival in breast cancer patients
Key clinical point: Extreme use of disease-monitoring tests significantly elevates health care costs and provides no survival benefit. Major...
Article
Adrenal gland tumors linked to ADHD diagnosis
Key clinical point: Pediatric patients with pheochromocytomas (PHEO) or paragangliomas (PGL) were more likely to also carry a diagnosis of ADHD,...
Article
Validated tool outperforms KPS in predicting chemo toxicity in older adults
Key clinical point: Investigators validated a mathematical model that successfully predicts chemotherapy toxicity in cancer patients aged 65 years...
News
Early palliative care for cancer patients benefits caregivers
Key clinical point: Early palliative care for cancer patients improved quality of life and lowered the incidence of depression for caregivers....
News
Pembrolizumab benefit holds long-term for some melanoma patients
Key clinical point: Pembrolizumab increases long-term survival in some patients with advanced melanoma. Major finding: The 3-year overall...
News
No benefit from added trabectedin for STS patients
Key clinical point: When trabectedin was administered to soft tissue sarcoma (STS) patients receiving doxorubicin, neither progression-free nor...
News
Gene variation affects survival benefits with cetuximab in colorectal cancer
Key clinical point: Patients with the H/H genotype in the FCGR2A gene have higher survival rates when treated with cetuximab than do patients with...